InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: PUS1

Summary

InnateDB Protein

IDBP-65097.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

PUS1

Protein Name

pseudouridylate synthase 1

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000324726

InnateDB Gene

IDBG-65093 (PUS1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 25 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	25 [view]
Protein-Protein	25 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003723	RNA binding
GO:0009982	pseudouridine synthase activity

Biological Process

GO:0001522	pseudouridine synthesis
GO:0009451	RNA modification

Cellular Component

Protein Structure and Domains

PDB ID

InterPro

IPR001406 Pseudouridine synthase I, TruA
IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain
IPR020103 Pseudouridine synthase, catalytic domain

PFAM

PF01416

PRINTS

PIRSF

PIRSF001430

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite