Homo sapiens Protein: ALDH5A1
Summary
InnateDB Protein IDBP-65288.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ALDH5A1
Protein Name aldehyde dehydrogenase 5 family, member A1
Synonyms SSADH; SSDH;
Species Homo sapiens
Ensembl Protein ENSP00000314649
InnateDB Gene IDBG-65286 (ALDH5A1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
Experimentally validated
Total 9 [view]
Protein-Protein 7 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004777 succinate-semialdehyde dehydrogenase (NAD+) activity
GO:0009013 succinate-semialdehyde dehydrogenase [NAD(P)+] activity
GO:0016491 oxidoreductase activity
GO:0042803 protein homodimerization activity
Biological Process
GO:0006006 glucose metabolic process
GO:0006083 acetate metabolic process
GO:0006105 succinate metabolic process
GO:0006536 glutamate metabolic process
GO:0006541 glutamine metabolic process
GO:0006650 glycerophospholipid metabolic process
GO:0006678 glucosylceramide metabolic process
GO:0006681 galactosylceramide metabolic process
GO:0006749 glutathione metabolic process
GO:0007268 synaptic transmission
GO:0007269 neurotransmitter secretion
GO:0007417 central nervous system development
GO:0008152 metabolic process
GO:0009448 gamma-aminobutyric acid metabolic process
GO:0009450 gamma-aminobutyric acid catabolic process
GO:0009791 post-embryonic development
GO:0022904 respiratory electron transport chain
GO:0042135 neurotransmitter catabolic process
GO:0046459 short-chain fatty acid metabolic process
GO:0051289 protein homotetramerization
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005739 mitochondrion
GO:0005759 mitochondrial matrix
Protein Structure and Domains
PDB ID
InterPro IPR010102 Succinate semialdehyde dehydrogenase
IPR015590 Aldehyde dehydrogenase domain
IPR016161 Aldehyde/histidinol dehydrogenase
PFAM PF00171
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P51649
PhosphoSite PhosphoSite-P51649
TrEMBL X5D299
UniProt Splice Variant
Entrez Gene 7915
UniGene Hs.640460
RefSeq NP_733936
HUGO HGNC:408
OMIM 610045
CCDS CCDS4556
HPRD 08361
IMGT
EMBL AJ427354 AJ427355 AK315380 AL031230 BC034321 CH471087 KJ534769 L34820 Y11192
GenPept AAA67057 AAH34321 AHW56409 BAG37773 CAA20248 CAA72076 CAD20883 CAD20884 EAW55452 EAW55453