InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: CACNG1

Summary

InnateDB Protein

IDBP-65327.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

CACNG1

Protein Name

calcium channel, voltage-dependent, gamma subunit 1

Synonyms

CACNLG;

Species

Homo sapiens

Ensembl Protein

ENSP00000226021

InnateDB Gene

IDBG-65325 (CACNG1)

Protein Structure

UniProt Annotation

Function

This protein is a subunit of the dihydropyridine (DHP) sensitive calcium channel. Plays a role in excitation-contraction coupling. The skeletal muscle DHP-sensitive Ca(2+) channel may function only as a multiple subunit complex.

Subcellular Localization

Membrane; Multi-pass membrane protein.

Disease Associations

Tissue Specificity

Skeletal muscle.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005245	voltage-gated calcium channel activity

Biological Process

GO:0006810	transport
GO:0006936	muscle contraction
GO:0034765	regulation of ion transmembrane transport
GO:0070296	sarcoplasmic reticulum calcium ion transport
GO:0070588	calcium ion transmembrane transport

Cellular Component

GO:0005891	voltage-gated calcium channel complex
GO:0016021	integral component of membrane

Protein Structure and Domains

PDB ID

InterPro

IPR004031 PMP-22/EMP/MP20/Claudin superfamily
IPR005421 Voltage-dependent calcium channel, gamma-1 subunit
IPR008368 Voltage-dependent calcium channel, gamma subunit

PFAM

PF00822
PF13903

PRINTS

PR01601
PR01792

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q06432