InnateDB Protein
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IDBP-65367.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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COMMD7
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Protein Name
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COMM domain containing 7
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000278980
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InnateDB Gene
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IDBG-65365 (COMMD7)
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Protein Structure
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Function |
Associates with the NF-kappa-B complex and suppresses its transcriptional activity. {ECO:0000269PubMed:15799966}.
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Subcellular Localization |
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Disease Associations |
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Tissue Specificity |
Widely expressed with highest expression in lung. {ECO:0000269PubMed:15799966}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
6
[view]
|
Protein-Protein |
6
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
GO:0032088
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negative regulation of NF-kappaB transcription factor activity
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GO:0033209
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tumor necrosis factor-mediated signaling pathway
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GO:0045892
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negative regulation of transcription, DNA-templated
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Cellular Component |
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PDB ID |
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InterPro |
IPR009886
HCaRG
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PFAM |
PF07258
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q86VX2
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PhosphoSite |
PhosphoSite-Q86VX2
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
149951
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UniGene |
Hs.408427
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RefSeq |
NP_444269
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HUGO |
HGNC:16223
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OMIM |
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CCDS |
CCDS42864
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HPRD |
13085
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IMGT |
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EMBL |
AK027893
AK096307
AL035071
AY542162
BC000628
BC047440
BI821799
BX640505
CH471077
FO393400
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GenPept |
AAH00628
AAH47440
AAS22244
BAB55436
BAG53254
EAW76360
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