Version 5.4
Homo sapiens Protein: NOL11
Summary
InnateDB Protein IDBP-65529.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NOL11
Protein Name nucleolar protein 11
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000253247
InnateDB Gene IDBG-65527 (NOL11)
Protein Structure
UniProt Annotation
Function Ribosome biogenesis factor. May be required for both optimal rDNA transcription and small subunit (SSU) pre-rRNA processing at sites A', A0, 1 and 2b. {ECO:0000269PubMed:22916032}.
Subcellular Localization Nucleus, nucleolus {ECO:0000269PubMed:12429849, ECO:0000269PubMed:22916032}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
Experimentally validated
Total 8 [view]
Protein-Protein 8 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0030490 maturation of SSU-rRNA
GO:1901838 positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0034455 t-UTP complex
Protein Structure and Domains
PDB ID
InterPro IPR012584 NUC205
PFAM PF08168
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9H8H0
PhosphoSite PhosphoSite-Q9H8H0
TrEMBL
UniProt Splice Variant
Entrez Gene 25926
UniGene Hs.463936
RefSeq NP_056277
HUGO HGNC:24557
OMIM 615366
CCDS CCDS11671
HPRD 10900
IMGT
EMBL AC006534 AK023702 AK299483 AL110271 AY598333 BC001726 BC064404
GenPept AAH01726 AAH64404 AAT06744 BAB14647 BAH13045 CAB53709

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca