InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: PXMP2

Summary

InnateDB Protein

IDBP-65876.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

PXMP2

Protein Name

peroxisomal membrane protein 2, 22kDa

Synonyms

PMP22;

Species

Homo sapiens

Ensembl Protein

ENSP00000321271

InnateDB Gene

IDBG-65904 (PXMP2)

Protein Structure

UniProt Annotation

Function

Seems to be involved in pore-forming activity and may contribute to the unspecific permeability of the peroxisomal membrane.

Subcellular Localization

Peroxisome membrane; Multi-pass membrane protein.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.

Experimentally validated
Total	5 [view]
Protein-Protein	5 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding

Biological Process

GO:0008150

biological_process

Cellular Component

GO:0005737	cytoplasm
GO:0005739	mitochondrion
GO:0005778	peroxisomal membrane
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0043234	protein complex

Protein Structure and Domains

PDB ID

InterPro

IPR007248 Mpv17/PMP22

PFAM

PF04117

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q9NR77

PhosphoSite

PhosphoSite-

TrEMBL

UniProt Splice Variant

Entrez Gene

5827

UniGene

RefSeq

NP_061133

HUGO

HGNC:9716

OMIM

CCDS

CCDS9279

HPRD

10176

IMGT

EMBL

AF250136 AY044439 BC073997

GenPept

AAF73963 AAH73997 AAK95858