InnateDB Protein
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IDBP-65933.7
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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FAM65B
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Protein Name
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family with sequence similarity 65, member B
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Synonyms
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C6orf32; DIFF40; DIFF48; MYONAP; PL48;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000367262
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InnateDB Gene
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IDBG-65927 (FAM65B)
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Protein Structure
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Function |
Isoform 2 play a role in promoting myogenic cell differentiation, cytoskeletal rearrangement and filopodia formation. {ECO:0000269PubMed:17150207}.
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Subcellular Localization |
Isoform 1: Mitochondrion.Isoform 2: Cytoplasm, cytoskeleton. Cell projection, filopodium. Note=Detected in cellular filopodia.
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Disease Associations |
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Tissue Specificity |
Isoform 1 is present in the brain. Isoform 2 is expressed during differentiation of fetal primary myoblasts. Also shows marked expression during cytotrophoblast differentiation. {ECO:0000269PubMed:17150207, ECO:0000269PubMed:9055809}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
8
[view]
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Protein-Protein |
8
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
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PFAM |
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q9Y4F9
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PhosphoSite |
PhosphoSite-Q9Y4F9
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TrEMBL |
A0A024R028
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UniProt Splice Variant |
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Entrez Gene |
9750
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UniGene |
Hs.559459
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RefSeq |
NP_056948
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HUGO |
HGNC:13872
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OMIM |
611410
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CCDS |
CCDS47384
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HPRD |
12881
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IMGT |
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EMBL |
AB002384
AL078584
AL512428
BC001232
CH471087
U49187
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GenPept |
AAC51134
AAH01232
BAA20840
CAH73086
CAH73087
CAI19934
CAI19935
EAW55467
EAW55469
EAW55470
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