Version 5.4
Homo sapiens Protein: TMEM126B
Summary
InnateDB Protein IDBP-66408.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TMEM126B
Protein Name transmembrane protein 126B
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000351737
InnateDB Gene IDBG-66406 (TMEM126B)
Protein Structure
UniProt Annotation
Function Chaperone protein involved in the assembly of the mitochondrial NADH:ubiquinone oxidoreductase complex (complex I). Participates in constructing the membrane arm of complex I. {ECO:0000269PubMed:24191001}.
Subcellular Localization Mitochondrion membrane {ECO:0000269PubMed:24191001}; Multi-pass membrane protein {ECO:0000269PubMed:24191001}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
Experimentally validated
Total 8 [view]
Protein-Protein 6 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
Biological Process
GO:0008150 biological_process
Cellular Component
GO:0005575 cellular_component
GO:0016021 integral component of membrane
GO:0031966 mitochondrial membrane
Protein Structure and Domains
PDB ID
InterPro IPR009801 Protein of unknown function DUF1370, TMEM126
PFAM PF07114
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8IUX1
PhosphoSite PhosphoSite-Q8IUX1
TrEMBL A0A024R5L4
UniProt Splice Variant
Entrez Gene 55863
UniGene
RefSeq NP_060950
HUGO HGNC:30883
OMIM 615533
CCDS CCDS8267
HPRD 13715
IMGT
EMBL AF220193 AK291150 AP000642 BC012065 BC017574 BC038933 BC107900 CH471076 CR612738
GenPept AAF67658 AAH12065 AAH17574 AAH38933 AAI07901 BAF83839 EAW75098 EAW75101

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca