Version 5.4
Homo sapiens Protein: ZNF350
Summary
InnateDB Protein IDBP-66451.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ZNF350
Protein Name zinc finger protein 350
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000243644
InnateDB Gene IDBG-544227 (ZNF350)
Protein Structure
UniProt Annotation
Function Transcriptional repressor. Binds to a specific sequence, 5'-GGGxxxCAGxxxTTT-3', within GADD45 intron 3. {ECO:0000269PubMed:11090615}.
Subcellular Localization Nucleus. Nucleus matrix. Note=Associated with the nuclear matrix.
Disease Associations
Tissue Specificity Widely expressed. {ECO:0000269PubMed:11161714}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
Experimentally validated
Total 10 [view]
Protein-Protein 9 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0016564 transcription repressor activity
GO:0046872 metal ion binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0016481 negative regulation of transcription
GO:0045892 negative regulation of transcription, DNA-templated
Cellular Component
GO:0005622 intracellular
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0016363 nuclear matrix
GO:0017053 transcriptional repressor complex
Protein Structure and Domains
PDB ID
InterPro IPR001909 Krueppel-associated box
IPR007087 Zinc finger, C2H2
IPR015880 Zinc finger, C2H2-like
PFAM PF01352
PF00096
PRINTS
PIRSF
SMART SM00349
SM00355
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9GZX5
PhosphoSite PhosphoSite-Q9GZX5
TrEMBL M0R1T8
UniProt Splice Variant
Entrez Gene 59348
UniGene Hs.407694
RefSeq NP_067645
HUGO HGNC:16656
OMIM 605422
CCDS CCDS12845
HPRD 05663
IMGT
EMBL AC011460 AF295096 AF309561 AK023467 BC009921 CH471135
GenPept AAG17439 AAG25714 AAH09921 BAB14583 EAW72056

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca