InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: CBFA2T2

Summary

InnateDB Protein

IDBP-66642.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

CBFA2T2

Protein Name

core-binding factor, runt domain, alpha subunit 2; translocated to, 2

Synonyms

EHT; MTGR1; p85; ZMYND3;

Species

Homo sapiens

Ensembl Protein

ENSP00000345810

InnateDB Gene

IDBG-66628 (CBFA2T2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 22 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	22 [view]
Protein-Protein	22 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0003714	transcription corepressor activity
GO:0005515	protein binding
GO:0046872	metal ion binding

Biological Process

GO:0006355	regulation of transcription, DNA-templated
GO:0010976	positive regulation of neuron projection development
GO:0010977	negative regulation of neuron projection development

Cellular Component

GO:0005634

nucleus

Protein Structure and Domains

PDB ID

InterPro

IPR002893 Zinc finger, MYND-type
IPR003894 TAFH/NHR1
IPR013289 Eight-Twenty-One
IPR013291 Myeloid transforming gene-related protein-1 (MTGR1)
IPR014896 NHR2-like

PFAM

PF01753
PF07531
PF08788

PRINTS

PR01875
PR01877

PIRSF

SMART

SM00549

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt