Homo sapiens Protein: KLHL6
Summary
InnateDB Protein IDBP-66988.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol KLHL6
Protein Name kelch-like 6 (Drosophila)
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000341342
InnateDB Gene IDBG-66986 (KLHL6)
Protein Structure
UniProt Annotation
Function Involved in B-lymphocyte antigen receptor signaling and germinal center formation. {ECO:0000250}.
Subcellular Localization
Disease Associations
Tissue Specificity Found in germinal center B-cells. {ECO:0000269PubMed:12617994}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
Experimentally validated
Total 6 [view]
Protein-Protein 5 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0002467 germinal center formation
GO:0050853 B cell receptor signaling pathway
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR000210 BTB/POZ-like
IPR006652 Kelch repeat type 1
IPR011333 BTB/POZ fold
IPR011498 Kelch repeat type 2
IPR011705 BTB/Kelch-associated
IPR013069 BTB/POZ
IPR017096 Kelch-like protein, gigaxonin type
PFAM PF01344
PF07646
PF07707
PF00651
PRINTS
PIRSF PIRSF037037
SMART SM00225
SM00612
SM00875
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8WZ60
PhosphoSite PhosphoSite-Q8WZ60
TrEMBL
UniProt Splice Variant
Entrez Gene 89857
UniGene Hs.659147
RefSeq NP_569713
HUGO HGNC:18653
OMIM 614214
CCDS CCDS3245
HPRD 10035
IMGT
EMBL AC069211 AC092960 AF441792 AK097125 AK314473 BC032348 CH471052
GenPept AAH32348 AAL35594 BAC04957 BAG37078 EAW78324 EAW78325