Version 5.4
Homo sapiens Protein: PRSS23
Summary
InnateDB Protein IDBP-67023.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PRSS23
Protein Name protease, serine, 23
Synonyms SIG13; SPUVE; ZSIG13;
Species Homo sapiens
Ensembl Protein ENSP00000280258
InnateDB Gene IDBG-67021 (PRSS23)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Secreted {ECO:0000305}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 28 experimentally validated interaction(s) in this database.
Experimentally validated
Total 28 [view]
Protein-Protein 27 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0004252 serine-type endopeptidase activity
Biological Process
GO:0006508 proteolysis
Cellular Component
GO:0005634 nucleus
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR001254 Peptidase S1
IPR009003 Trypsin-like cysteine/serine peptidase domain
PFAM PF00089
PRINTS
PIRSF
SMART SM00020
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O95084
PhosphoSite PhosphoSite-O95084
TrEMBL E9PRR2
UniProt Splice Variant
Entrez Gene 11098
UniGene Hs.729257
RefSeq NP_009104
HUGO HGNC:14370
OMIM
CCDS CCDS8278
HPRD 07149
IMGT
EMBL AF015287 AF193611 AK315562 AK316508 AL136914 AP000654 AP001528 AY359033 BC001278 CH471076 CR456824
GenPept AAD01553 AAF07186 AAH01278 AAQ89392 BAG37938 BAH14879 CAB66848 CAG33105 EAW75145

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca