Version 5.4
Homo sapiens Protein: KIF19
Summary
InnateDB Protein IDBP-67089.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol KIF19
Protein Name kinesin family member 19
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000374566
InnateDB Gene IDBG-67081 (KIF19)
Protein Structure
UniProt Annotation
Function Plus end-directed microtubule-dependent motor protein that regulates the length of motile cilia by mediating depolymerization of microtubules at ciliary tips. {ECO:0000250}.
Subcellular Localization Cytoplasm, cytoskeleton {ECO:0000250}. Cell projection, cilium {ECO:0000250}. Note=Localizes to cilia tips. {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003777 microtubule motor activity
GO:0005524 ATP binding
GO:0008017 microtubule binding
GO:0008574 plus-end-directed microtubule motor activity
Biological Process
GO:0007018 microtubule-based movement
GO:0008152 metabolic process
GO:0060404 axonemal microtubule depolymerization
GO:0070462 plus-end specific microtubule depolymerization
Cellular Component
GO:0005737 cytoplasm
GO:0005871 kinesin complex
GO:0005874 microtubule
GO:0005929 cilium
Protein Structure and Domains
PDB ID
InterPro IPR001752 Kinesin, motor domain
IPR027417 P-loop containing nucleoside triphosphate hydrolase
PFAM PF00225
PRINTS PR00380
PIRSF
SMART SM00129
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q2TAC6
PhosphoSite PhosphoSite-Q2TAC6
TrEMBL
UniProt Splice Variant
Entrez Gene 124602
UniGene Hs.372773
RefSeq NP_694941
HUGO HGNC:26735
OMIM
CCDS CCDS32718
HPRD 08782
IMGT
EMBL AC055863 AC103809 AK094619 BC093631 BC104852 BC110989 BC143327 CH471099
GenPept AAH93631 AAI04853 AAI10990 AAI43328 BAC04386 EAW89153

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca