InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: CD300C

Summary

InnateDB Protein

IDBP-67338.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

CD300C

Protein Name

CD300c molecule

Synonyms

CLM-6; CMRF-35; CMRF-35A; CMRF35; CMRF35-A1; CMRF35A; CMRF35A1; IGSF16; LIR;

Species

Homo sapiens

Ensembl Protein

ENSP00000329507

InnateDB Gene

IDBG-67336 (CD300C)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Cell membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.

Disease Associations

Tissue Specificity

Present on the surface of monocytes, neutrophils, a proportion of peripheral blood T- and B-lymphocytes and lymphocytic cell lines.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.

Experimentally validated
Total	3 [view]
Protein-Protein	3 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004888	transmembrane signaling receptor activity
GO:0005515	protein binding

Biological Process

GO:0002376	immune system process
GO:0006968	cellular defense response
GO:0007165	signal transduction

Cellular Component

GO:0005887

integral component of plasma membrane

Protein Structure and Domains

PDB ID

InterPro

IPR003599 Immunoglobulin subtype
IPR007110 Immunoglobulin-like domain
IPR013106 Immunoglobulin V-set domain

PFAM

PF07686

PRINTS

PIRSF

SMART

SM00409

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q08708

PhosphoSite

PhosphoSite-Q08708

TrEMBL

UniProt Splice Variant

Entrez Gene

10871

UniGene

RefSeq

NP_006669

HUGO

HGNC:19320

OMIM

606786

CCDS

CCDS11701

HPRD

09491

IMGT

EMBL

AF373863 AF373864 AF373865 AF373866 BC022279 X66171

GenPept

AAH22279 AAK64272 CAA46948