InnateDB Protein
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IDBP-67440.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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KIF5B
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Protein Name
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kinesin family member 5B
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Synonyms
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HEL-S-61; KINH; KNS; KNS1; UKHC;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000307078
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InnateDB Gene
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IDBG-67436 (KIF5B)
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Protein Structure
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Function |
Microtubule-dependent motor required for normal distribution of mitochondria and lysosomes. {ECO:0000250}.
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Subcellular Localization |
Cytoplasm, cytoskeleton {ECO:0000250}. Note=Uniformly distributed between soma and neurites in hippocampal neurons. {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 77 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
Experimentally validated |
Total |
77
[view]
|
Protein-Protein |
77
[view]
|
Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
9 [view]
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Molecular Function |
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Biological Process |
GO:0007018
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microtubule-based movement
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GO:0007028
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cytoplasm organization
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GO:0035617
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stress granule disassembly
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GO:0042391
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regulation of membrane potential
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GO:0043268
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positive regulation of potassium ion transport
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GO:0044267
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cellular protein metabolic process
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GO:0047496
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vesicle transport along microtubule
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GO:0072383
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plus-end-directed vesicle transport along microtubule
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GO:0090004
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positive regulation of establishment of protein localization to plasma membrane
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Cellular Component |
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PDB ID |
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InterPro |
IPR001752
Kinesin, motor domain
IPR027417
P-loop containing nucleoside triphosphate hydrolase
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PFAM |
PF00225
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PRINTS |
PR00380
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PIRSF |
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SMART |
SM00129
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TIGRFAMs |
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Modification |
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SwissProt |
P33176
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PhosphoSite |
PhosphoSite-P33176
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TrEMBL |
V9HW29
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UniProt Splice Variant |
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Entrez Gene |
3799
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UniGene |
Hs.327736
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RefSeq |
NP_004512
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HUGO |
HGNC:6324
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OMIM |
602809
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CCDS |
CCDS7171
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HPRD |
07214
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IMGT |
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EMBL |
AK289413
AL161932
BC126279
BC126281
FJ224324
X65873
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GenPept |
AAI26280
AAI26282
ACI46016
BAF82102
CAA46703
CAH71618
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