InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: ATP6V0E1

Summary

InnateDB Protein

IDBP-679861.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ATP6V0E1

Protein Name

V-type proton ATPase subunit e 1

Synonyms

ATP6V0E;

Species

Bos taurus

Ensembl Protein

ENSBTAP00000020094

InnateDB Gene

IDBG-628498 (ATP6V0E1)

Protein Structure

UniProt Annotation

Function

Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.

Subcellular Localization

Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.

Disease Associations

Tissue Specificity

Expressed in lung, heart, spleen, kidney and adrenal gland. Not found in brain.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0015078	hydrogen ion transmembrane transporter activity
GO:0016787	hydrolase activity

Biological Process

GO:0006810	transport
GO:0006811	ion transport
GO:0008152	metabolic process
GO:0015991	ATP hydrolysis coupled proton transport
GO:0015992	proton transport
GO:0016049	cell growth

Cellular Component

GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0033179	proton-transporting V-type ATPase, V0 domain

Protein Structure and Domains

PDB ID

InterPro

IPR008389 ATPase, V0 complex, subunit e1/e2
IPR017385 ATPase, V0 complex, subunit e1/e2, metazoa

PFAM

PF05493

PRINTS

PIRSF

PIRSF038097

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

P81103

PhosphoSite

PhosphoSite-

TrEMBL

UniProt Splice Variant

Entrez Gene

338075

UniGene

Bt.2450

RefSeq

NP_001029222

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

BC103204 Y15285

GenPept

AAI03205 CAA75570