InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: GABRB3

Summary

InnateDB Protein

IDBP-679924.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

GABRB3

Protein Name

gamma-aminobutyric acid receptor subunit beta-3

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000017858

InnateDB Gene

IDBG-628556 (GABRB3)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.

Predicted by orthology
Total	4 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004890	GABA-A receptor activity
GO:0005216	ion channel activity
GO:0005230	extracellular ligand-gated ion channel activity

Biological Process

GO:0006810	transport
GO:0006811	ion transport
GO:0007165	signal transduction
GO:0007605	sensory perception of sound
GO:0034220	ion transmembrane transport
GO:0043523	regulation of neuron apoptotic process
GO:0043524	negative regulation of neuron apoptotic process
GO:0048666	neuron development
GO:0060119	inner ear receptor cell development
GO:0060384	innervation
GO:0071420	cellular response to histamine
GO:0090102	cochlea development
GO:1901215	negative regulation of neuron death

Cellular Component

GO:0005886	plasma membrane
GO:0005887	integral component of plasma membrane
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0030054	cell junction
GO:0045202	synapse

Protein Structure and Domains

PDB ID

InterPro

IPR002289 Gamma-aminobutyric-acid A receptor, beta subunit
IPR006028 Gamma-aminobutyric acid A receptor/Glycine receptor alpha
IPR006029 Neurotransmitter-gated ion-channel transmembrane domain
IPR006201 Neurotransmitter-gated ion-channel
IPR006202 Neurotransmitter-gated ion-channel ligand-binding

PFAM

PF02932
PF02931

PRINTS

PR01160
PR00253
PR00252

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite