Version 5.4
Bos taurus Protein: MTUS1
Summary
InnateDB Protein IDBP-680045.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MTUS1
Protein Name Microtubule-associated tumor suppressor 1 homolog
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000002556
InnateDB Gene IDBG-628656 (MTUS1)
Protein Structure
UniProt Annotation
Function Cooperates with AGTR2 to inhibit ERK2 activation and cell proliferation. May be required for AGTR2 cell surface expression. Together with PTPN6, induces UBE2V2 expression upon angiotensin-II stimulation (By similarity). {ECO:0000250}.
Subcellular Localization Mitochondrion {ECO:0000250}. Golgi apparatus {ECO:0000250}. Cell membrane {ECO:0000250}. Nucleus {ECO:0000250}. Note=In neurons, translocates into the nucleus after treatment with angiotensin-II. {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0007049 cell cycle
Cellular Component
GO:0005634 nucleus
GO:0005739 mitochondrion
GO:0005794 Golgi apparatus
GO:0005886 plasma membrane
GO:0016020 membrane
Protein Structure and Domains
PDB ID
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q17QT2
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 515016
UniGene Bt.37983
RefSeq NP_001069160
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC118198
GenPept AAI18199

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca