Bos taurus Protein: MSR1
Summary
InnateDB Protein IDBP-680096.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MSR1
Protein Name Macrophage scavenger receptor types I and II
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000003755
InnateDB Gene IDBG-628711 (MSR1)
Protein Structure
UniProt Annotation
Function Membrane glycoproteins implicated in the pathologic deposition of cholesterol in arterial walls during atherogenesis. Two types of receptor subunits exist. These receptors mediate the endocytosis of a diverse group of macromolecules, including modified low density lipoproteins (LDL).
Subcellular Localization Membrane; Single-pass type II membrane protein.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0004871 signal transducer activity
GO:0005044 scavenger receptor activity
Biological Process
GO:0006355 regulation of transcription, DNA-templated
GO:0006897 endocytosis
GO:0006898 receptor-mediated endocytosis
GO:0007165 signal transduction
Cellular Component
GO:0005581 collagen trimer
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0034362 low-density lipoprotein particle
Protein Structure and Domains
PDB ID
InterPro IPR003543 Macrophage scavenger receptor
IPR008160 Collagen triple helix repeat
IPR015988 STAT transcription factor, coiled coil
PFAM PF03523
PF01391
PRINTS PR01408
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P21758
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 281311
UniGene Bt.4482
RefSeq NP_776538
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC142250 X51689 X54183
GenPept AAI42251 CAA35987 CAA38108