Bos taurus Protein: RET
Summary
InnateDB Protein IDBP-680127.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RET
Protein Name ret proto-oncogene
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000000744
InnateDB Gene IDBG-628722 (RET)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 29 interaction(s) predicted by orthology.
Predicted by orthology
Total 29 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0004672 protein kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016301 kinase activity
GO:0016740 transferase activity
GO:0016772 transferase activity, transferring phosphorus-containing groups
Biological Process
GO:0000165 MAPK cascade
GO:0001657 ureteric bud development
GO:0001755 neural crest cell migration
GO:0001838 embryonic epithelial tube formation
GO:0006468 protein phosphorylation
GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0007156 homophilic cell adhesion
GO:0007158 neuron cell-cell adhesion
GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
GO:0007399 nervous system development
GO:0010976 positive regulation of neuron projection development
GO:0016310 phosphorylation
GO:0018108 peptidyl-tyrosine phosphorylation
GO:0030155 regulation of cell adhesion
GO:0030182 neuron differentiation
GO:0030335 positive regulation of cell migration
GO:0033619 membrane protein proteolysis
GO:0033630 positive regulation of cell adhesion mediated by integrin
GO:0035799 ureter maturation
GO:0042551 neuron maturation
GO:0045793 positive regulation of cell size
GO:0045893 positive regulation of transcription, DNA-templated
GO:0048265 response to pain
GO:0048484 enteric nervous system development
GO:0050770 regulation of axonogenesis
GO:0061146 Peyer's patch morphogenesis
GO:0071300 cellular response to retinoic acid
GO:0072300 positive regulation of metanephric glomerulus development
GO:2001241 positive regulation of extrinsic apoptotic signaling pathway in absence of ligand
Cellular Component
GO:0005887 integral component of plasma membrane
GO:0010008 endosome membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0043235 receptor complex
Protein Structure and Domains
PDB ID
InterPro IPR000719 Protein kinase domain
IPR001245 Serine-threonine/tyrosine-protein kinase catalytic domain
IPR002126 Cadherin
IPR002290 Serine/threonine/dual specificity protein kinase, catalytic domain
IPR011009 Protein kinase-like domain
IPR015919 Cadherin-like
IPR016249 Tyrosine-protein kinase, Ret receptor
IPR020635 Tyrosine-protein kinase, catalytic domain
PFAM PF00069
PF07714
PF00028
PRINTS PR00109
PR00205
PIRSF PIRSF000631
SMART SM00112
SM00220
SM00219
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL F1MS00
UniProt Splice Variant
Entrez Gene 515924
UniGene Bt.55314
RefSeq NP_001178412
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02061567
GenPept