InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: NRG1

Summary

InnateDB Protein

IDBP-680336.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

NRG1

Protein Name

neuregulin 1

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000044846

InnateDB Gene

IDBG-628923 (NRG1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.

Predicted by orthology
Total	6 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003712	transcription cofactor activity
GO:0005102	receptor binding
GO:0005176	ErbB-2 class receptor binding
GO:0005515	protein binding
GO:0008083	growth factor activity
GO:0030296	protein tyrosine kinase activator activity
GO:0043125	ErbB-3 class receptor binding

Biological Process

GO:0000165	MAPK cascade
GO:0000902	cell morphogenesis
GO:0003161	cardiac conduction system development
GO:0003222	ventricular trabecula myocardium morphogenesis
GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
GO:0007399	nervous system development
GO:0007416	synapse assembly
GO:0007422	peripheral nervous system development
GO:0007507	heart development
GO:0007517	muscle organ development
GO:0007626	locomotory behavior
GO:0008283	cell proliferation
GO:0009790	embryo development
GO:0010001	glial cell differentiation
GO:0010667	negative regulation of cardiac muscle cell apoptotic process
GO:0016477	cell migration
GO:0021781	glial cell fate commitment
GO:0030307	positive regulation of cell growth
GO:0038127	ERBB signaling pathway
GO:0042060	wound healing
GO:0042177	negative regulation of protein catabolic process
GO:0043497	regulation of protein heterodimerization activity
GO:0043624	cellular protein complex disassembly
GO:0045213	neurotransmitter receptor metabolic process
GO:0045595	regulation of cell differentiation
GO:0045785	positive regulation of cell adhesion
GO:0045860	positive regulation of protein kinase activity
GO:0045892	negative regulation of transcription, DNA-templated
GO:0046579	positive regulation of Ras protein signal transduction
GO:0048663	neuron fate commitment
GO:0051048	negative regulation of secretion
GO:0051897	positive regulation of protein kinase B signaling
GO:0055012	ventricular cardiac muscle cell differentiation
GO:0060045	positive regulation of cardiac muscle cell proliferation
GO:0060379	cardiac muscle cell myoblast differentiation
GO:0060956	endocardial cell differentiation
GO:0061098	positive regulation of protein tyrosine kinase activity
GO:2001240	negative regulation of extrinsic apoptotic signaling pathway in absence of ligand

Cellular Component

GO:0005615	extracellular space
GO:0005737	cytoplasm
GO:0005886	plasma membrane
GO:0005887	integral component of plasma membrane
GO:0016324	apical plasma membrane
GO:0030424	axon
GO:0031594	neuromuscular junction
GO:0045202	synapse