Bos taurus Protein: PLRG1
Summary
InnateDB Protein IDBP-680376.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PLRG1
Protein Name Pleiotropic regulator 1
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000029840
InnateDB Gene IDBG-628984 (PLRG1)
Protein Structure
UniProt Annotation
Function Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. {ECO:0000250}.
Subcellular Localization Nucleus {ECO:0000250}. Nucleus speckle {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 31 interaction(s) predicted by orthology.
Predicted by orthology
Total 31 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0006397 mRNA processing
GO:0008380 RNA splicing
GO:0034504 protein localization to nucleus
GO:1900087 positive regulation of G1/S transition of mitotic cell cycle
Cellular Component
GO:0005634 nucleus
GO:0005681 spliceosomal complex
GO:0016607 nuclear speck
GO:0071013 catalytic step 2 spliceosome
Protein Structure and Domains
PDB ID
InterPro IPR001680 WD40 repeat
IPR017986 WD40-repeat-containing domain
IPR020472 G-protein beta WD-40 repeat
PFAM PF00400
PRINTS PR00320
PIRSF
SMART SM00320
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q2KID6
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 533951
UniGene Bt.74313
RefSeq NP_001039827
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC112677
GenPept AAI12678