InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: FA2H

Summary

InnateDB Protein

IDBP-680377.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

FA2H

Protein Name

fatty acid 2-hydroxylase

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000016212

InnateDB Gene

IDBG-628991 (FA2H)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005506	iron ion binding
GO:0016491	oxidoreductase activity
GO:0020037	heme binding
GO:0080132	fatty acid alpha-hydroxylase activity

Biological Process

GO:0001949	sebaceous gland cell differentiation
GO:0006631	fatty acid metabolic process
GO:0006633	fatty acid biosynthetic process
GO:0006665	sphingolipid metabolic process
GO:0030258	lipid modification
GO:0032286	central nervous system myelin maintenance
GO:0032287	peripheral nervous system myelin maintenance
GO:0042127	regulation of cell proliferation
GO:0042634	regulation of hair cycle
GO:0055114	oxidation-reduction process

Cellular Component

GO:0005783

endoplasmic reticulum

Protein Structure and Domains

PDB ID

InterPro

IPR001199 Cytochrome b5-like heme/steroid binding domain
IPR006694 Fatty acid hydroxylase
IPR014430 Inositolphosphorylceramide-B hydroxylase

PFAM

PF00173
PF04116

PRINTS

PR00363

PIRSF

PIRSF005149

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

E1BGC2

UniProt Splice Variant

Entrez Gene

516891

UniGene

Bt.56808

RefSeq

NP_001179384

HUGO

HGNC:21197

OMIM

CCDS

HPRD

IMGT

EMBL

DAAA02045984

GenPept