Version 5.4
| Bos taurus Protein: RLBP1 | |||||||||
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| Summary | |||||||||
| InnateDB Protein | IDBP-680418.2 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | RLBP1 | ||||||||
| Protein Name | Retinaldehyde-binding protein 1 | ||||||||
| Synonyms | CRALBP; | ||||||||
| Species | Bos taurus | ||||||||
| Ensembl Protein | ENSBTAP00000045055 | ||||||||
| InnateDB Gene | IDBG-629024 (RLBP1) | ||||||||
| Protein Structure |
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| UniProt Annotation | |||||||||
| Function | Soluble retinoid carrier essential the proper function of both rod and cone photoreceptors. Participates in the regeneration of active 11-cis-retinol and 11-cis-retinaldehyde, from the inactive 11-trans products of the rhodopsin photocycle and in the de novo synthesis of these retinoids from 11-trans metabolic precursors. The cycling of retinoids between photoreceptor and adjacent pigment epithelium cells is known as the 'visual cycle'. | ||||||||
| Subcellular Localization | Cytoplasm. | ||||||||
| Disease Associations | |||||||||
| Tissue Specificity | Retina and pineal gland. | ||||||||
| Comments | |||||||||
| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||||||
| PDB ID | |||||||||
| InterPro |
IPR001071
Cellular retinaldehyde binding/alpha-tocopherol transport IPR001251 CRAL-TRIO domain IPR011074 CRAL/TRIO, N-terminal domain |
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| PFAM |
PF00650
PF13716 PF03765 |
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| PRINTS |
PR00180
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| PIRSF | |||||||||
| SMART |
SM00516
SM01100 |
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| TIGRFAMs | |||||||||
| Post-translational Modifications | |||||||||
| Modification | |||||||||
| Cross-References | |||||||||
| SwissProt | P10123 | ||||||||
| PhosphoSite | PhosphoSite- | ||||||||
| TrEMBL | |||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 282038 | ||||||||
| UniGene | Bt.88426 | ||||||||
| RefSeq | NP_776876 | ||||||||
| HUGO | |||||||||
| OMIM | |||||||||
| CCDS | |||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | BC118140 J04214 | ||||||||
| GenPept | AAA30751 AAI18141 | ||||||||