InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: ITM2B

Summary

InnateDB Protein

IDBP-680467.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ITM2B

Protein Name

integral membrane protein 2B

Synonyms

Bri; imBRI2;

Species

Bos taurus

Ensembl Protein

ENSBTAP00000004044

InnateDB Gene

IDBG-629079 (ITM2B)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0001540	beta-amyloid binding
GO:0005515	protein binding
GO:0005524	ATP binding

Biological Process

GO:0042985	negative regulation of amyloid precursor protein biosynthetic process
GO:0097192	extrinsic apoptotic signaling pathway in absence of ligand

Cellular Component

GO:0005615	extracellular space
GO:0005794	Golgi apparatus
GO:0005886	plasma membrane
GO:0016020	membrane
GO:0030660	Golgi-associated vesicle membrane
GO:0031301	integral component of organelle membrane
GO:0043231	intracellular membrane-bounded organelle
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

InterPro

IPR007084 BRICHOS domain

PFAM

PF04089

PRINTS

PIRSF

SMART

SM01039

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

F1N026

UniProt Splice Variant

Entrez Gene

510575

UniGene

RefSeq

NP_001030265

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

DAAA02032880 DAAA02032881

GenPept