Version 5.4
Bos taurus Protein: DYNLRB2
Summary
InnateDB Protein IDBP-680728.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DYNLRB2
Protein Name Dynein light chain roadblock-type 2
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000023603
InnateDB Gene IDBG-629324 (DYNLRB2)
Protein Structure
UniProt Annotation
Function Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules (By similarity). {ECO:0000250}.
Subcellular Localization Cytoplasm, cytoskeleton {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003774 motor activity
GO:0005515 protein binding
Biological Process
GO:0006810 transport
GO:0008152 metabolic process
Cellular Component
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
GO:0005868 cytoplasmic dynein complex
GO:0005874 microtubule
GO:0030286 dynein complex
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR004942 Dynein light chain-related
IPR016561 Dynein light chain, roadblock-type
PFAM PF03259
PRINTS
PIRSF PIRSF009998
SMART SM00960
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q32P85
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 768062
UniGene
RefSeq NP_001070587
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC108217
GenPept AAI08218

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca