Version 5.4
Bos taurus Protein: DYNLL2
Summary
InnateDB Protein IDBP-680730.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DYNLL2
Protein Name Dynein light chain 2, cytoplasmic
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000006190
InnateDB Gene IDBG-629328 (DYNLL2)
Protein Structure
UniProt Annotation
Function Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May be involved in some aspects of dynein-related intracellular transport and motility. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures (By similarity). {ECO:0000250}.
Subcellular Localization Cytoplasm, cytoskeleton {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 22 interaction(s) predicted by orthology.
Predicted by orthology
Total 22 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003774 motor activity
GO:0005515 protein binding
Biological Process
GO:0006810 transport
GO:0007017 microtubule-based process
GO:0008152 metabolic process
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005813 centrosome
GO:0005856 cytoskeleton
GO:0005874 microtubule
GO:0005875 microtubule associated complex
GO:0016020 membrane
GO:0016459 myosin complex
GO:0030286 dynein complex
Protein Structure and Domains
PDB ID
InterPro IPR001372 Dynein light chain, type 1/2
PFAM PF01221
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q3MHR3
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 540369
UniGene Bt.51543
RefSeq NP_001106774
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC105140
GenPept AAI05141

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca