InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: HTRA4

Summary

InnateDB Protein

IDBP-680797.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

HTRA4

Protein Name

HtrA serine peptidase 4

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000004564

InnateDB Gene

IDBG-629361 (HTRA4)

Protein Structure

UniProt Annotation

Function

Serine protease. {ECO:0000250}.

Subcellular Localization

Secreted {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003824	catalytic activity
GO:0004175	endopeptidase activity
GO:0004252	serine-type endopeptidase activity
GO:0005515	protein binding
GO:0005520	insulin-like growth factor binding
GO:0008233	peptidase activity
GO:0008236	serine-type peptidase activity
GO:0016787	hydrolase activity

Biological Process

GO:0001558	regulation of cell growth
GO:0006508	proteolysis

Cellular Component

GO:0005576

extracellular region

Protein Structure and Domains

PDB ID

InterPro

IPR000867 Insulin-like growth factor-binding protein, IGFBP
IPR001254 Peptidase S1
IPR001478 PDZ domain
IPR001940 Peptidase S1C
IPR002350 Kazal domain
IPR009003 Trypsin-like cysteine/serine peptidase domain

PFAM

PF00219
PF00089
PF00595
PF13180
PF00050
PF07648

PRINTS

PR00834

PIRSF

SMART

SM00121
SM00020
SM00228
SM00280

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt