InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: ITGA2

Summary

InnateDB Protein

IDBP-680813.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ITGA2

Protein Name

integrin alpha-2

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000025685

InnateDB Gene

IDBG-629414 (ITGA2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 20 interaction(s) predicted by orthology.

Predicted by orthology
Total	20 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0005518	collagen binding
GO:0038064	collagen receptor activity

Biological Process

GO:0006929	substrate-dependent cell migration
GO:0007155	cell adhesion
GO:0007160	cell-matrix adhesion
GO:0007229	integrin-mediated signaling pathway
GO:0031589	cell-substrate adhesion
GO:0033627	cell adhesion mediated by integrin
GO:0038065	collagen-activated signaling pathway

Cellular Component

GO:0005886	plasma membrane
GO:0005925	focal adhesion
GO:0008305	integrin complex
GO:0009897	external side of plasma membrane
GO:0009986	cell surface
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0045178	basal part of cell

Protein Structure and Domains

PDB ID

InterPro

IPR000413 Integrin alpha chain
IPR002035 von Willebrand factor, type A
IPR013517 FG-GAP repeat
IPR013519 Integrin alpha beta-propellor
IPR013649 Integrin alpha-2

PFAM

PF00092
PF01839
PF14312
PF08441

PRINTS

PR01185

PIRSF

SMART

SM00327
SM00191

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt