Version 5.4
Bos taurus Protein: TAC1
Summary
InnateDB Protein IDBP-680822.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TAC1
Protein Name Protachykinin-1Substance PNeurokinin ANeuropeptide KNeuropeptide gammaC-terminal-flanking peptide
Synonyms beta-PPT-A; PPT; TAC;
Species Bos taurus
Ensembl Protein ENSBTAP00000020419
InnateDB Gene IDBG-629411 (TAC1)
Protein Structure
UniProt Annotation
Function Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles.
Subcellular Localization Secreted.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
Predicted by orthology
Total 9 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0006954 inflammatory response
GO:0007204 positive regulation of cytosolic calcium ion concentration
GO:0007217 tachykinin receptor signaling pathway
GO:0007218 neuropeptide signaling pathway
GO:0007268 synaptic transmission
GO:0019233 sensory perception of pain
GO:0048265 response to pain
Cellular Component
GO:0005576 extracellular region
GO:0030424 axon
GO:0043025 neuronal cell body
Protein Structure and Domains
PDB ID
InterPro IPR008215 Tachykinin
IPR008216 Protachykinin
PFAM
PRINTS PR01829
PIRSF
SMART SM00203
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P01289
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 281512
UniGene
RefSeq NP_776618
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC142365 BC151422 M68911 M68912 X00075 X00076 X01396 X01397 X01398 X01399 X01400 X02351
GenPept AAA30724 AAA30725 AAI42366 AAI51423 CAA24939 CAA24940 CAA24941 CAA24942 CAA24943 CAA26206

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca