InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: ASNS

Summary

InnateDB Protein

IDBP-680837.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ASNS

Protein Name

Asparagine synthetase

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000004181

InnateDB Gene

IDBG-629426 (ASNS)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 22 interaction(s) predicted by orthology.

Predicted by orthology
Total	22 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0004066	asparagine synthase (glutamine-hydrolyzing) activity
GO:0005524	ATP binding
GO:0016874	ligase activity

Biological Process

GO:0006529	asparagine biosynthetic process
GO:0006541	glutamine metabolic process
GO:0008152	metabolic process
GO:0008652	cellular amino acid biosynthetic process
GO:0042149	cellular response to glucose starvation
GO:0043066	negative regulation of apoptotic process
GO:0045931	positive regulation of mitotic cell cycle
GO:0070981	L-asparagine biosynthetic process

Cellular Component

Protein Structure and Domains

PDB ID

InterPro

IPR000583 Class II glutamine amidotransferase domain
IPR001962 Asparagine synthase
IPR006426 Asparagine synthase, glutamine-hydrolyzing
IPR029055 Nucleophile aminohydrolases, N-terminal

PFAM

PF00310
PF13537
PF00733

PRINTS

PIRSF

PIRSF001589

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q1LZA3