Version 5.4
Bos taurus Protein: H2AFY2
Summary
InnateDB Protein IDBP-681031.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol H2AFY2
Protein Name H2A histone family, member Y2
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000001547
InnateDB Gene IDBG-629628 (H2AFY2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.
Predicted by orthology
Total 10 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0031490 chromatin DNA binding
GO:0044212 transcription regulatory region DNA binding
GO:0046982 protein heterodimerization activity
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0006334 nucleosome assembly
GO:0007420 brain development
GO:0007549 dosage compensation
GO:0045814 negative regulation of gene expression, epigenetic
GO:0071169 establishment of protein localization to chromatin
GO:1901837 negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter
Cellular Component
GO:0000786 nucleosome
GO:0000790 nuclear chromatin
GO:0001740 Barr body
GO:0005634 nucleus
GO:0005694 chromosome
GO:0035098 ESC/E(Z) complex
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR002119 Histone H2A
IPR002589 Macro domain
IPR007125 Histone core
IPR009072 Histone-fold
IPR021171 Core histone macro-H2A
PFAM PF01661
PF00125
PRINTS PR00620
PIRSF PIRSF037942
SMART SM00414
SM00506
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q1LZ92
UniProt Splice Variant
Entrez Gene 537167
UniGene Bt.74437
RefSeq NP_001069554
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC116136 DAAA02061840
GenPept AAI16137

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca