Version 5.4
Bos taurus Protein: GINS4
Summary
InnateDB Protein IDBP-681052.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GINS4
Protein Name DNA replication complex GINS protein SLD5
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000022773
InnateDB Gene IDBG-629643 (GINS4)
Protein Structure
UniProt Annotation
Function The GINS complex plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS4 is important for GINS complex assembly. GINS complex seems to bind preferentially to single-stranded DNA (By similarity). {ECO:0000250}.
Subcellular Localization Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 18 interaction(s) predicted by orthology.
Predicted by orthology
Total 18 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0006260 DNA replication
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID
InterPro IPR008591 GINS complex, subunit Sld5
IPR021151 GINS complex
PFAM PF05916
PRINTS
PIRSF PIRSF007764
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt A2VE40
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 616799
UniGene Bt.48705
RefSeq NP_001075929
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC133560
GenPept AAI33561

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca