InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: FOXO1

Summary

InnateDB Protein

IDBP-681053.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

FOXO1

Protein Name

forkhead box O1

Synonyms

FOXO1A;

Species

Bos taurus

Ensembl Protein

ENSBTAP00000053389

InnateDB Gene

IDBG-629639 (FOXO1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 40 interaction(s) predicted by orthology.

Predicted by orthology
Total	40 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000989	transcription factor binding transcription factor activity
GO:0001078	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
GO:0003677	DNA binding
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0005515	protein binding
GO:0031625	ubiquitin protein ligase binding
GO:0043565	sequence-specific DNA binding
GO:0051721	protein phosphatase 2A binding

Biological Process

GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0001568	blood vessel development
GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0006915	apoptotic process
GO:0006974	cellular response to DNA damage stimulus
GO:0008286	insulin receptor signaling pathway
GO:0009267	cellular response to starvation
GO:0010508	positive regulation of autophagy
GO:0032869	cellular response to insulin stimulus
GO:0032873	negative regulation of stress-activated MAPK cascade
GO:0034599	cellular response to oxidative stress
GO:0035947	regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter
GO:0042127	regulation of cell proliferation
GO:0042593	glucose homeostasis
GO:0043065	positive regulation of apoptotic process
GO:0043066	negative regulation of apoptotic process
GO:0045599	negative regulation of fat cell differentiation
GO:0045722	positive regulation of gluconeogenesis
GO:0045732	positive regulation of protein catabolic process
GO:0045893	positive regulation of transcription, DNA-templated
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0071455	cellular response to hyperoxia
GO:0071732	cellular response to nitric oxide