Version 5.4
Bos taurus Protein: HSBP1
Summary
InnateDB Protein IDBP-681098.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol HSBP1
Protein Name Heat shock factor-binding protein 1
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000034543
InnateDB Gene IDBG-629682 (HSBP1)
Protein Structure
UniProt Annotation
Function Negative regulator of the heat shock response. Negatively affects HSF1 DNA-binding activity. May have a role in the suppression of the activation of the stress response during the aging process (By similarity). {ECO:0000250}.
Subcellular Localization Nucleus {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Predicted by orthology
Total 7 [view]
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR009643 Heat shock factor binding 1
PFAM PF06825
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q3ZC22
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 767979
UniGene
RefSeq NP_001106787
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC102970
GenPept AAI02971

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca