Version 5.4
Bos taurus Protein: ETV1
Summary
InnateDB Protein IDBP-681179.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ETV1
Protein Name ETS translocation variant 1
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000021259
InnateDB Gene IDBG-629760 (ETV1)
Protein Structure
UniProt Annotation
Function Transcriptional activator that binds to DNA sequences containing the consensus pentanucleotide 5'-CGGA[AT]-3'. {ECO:0000250}.
Subcellular Localization Nucleus {ECO:0000255PROSITE- ProRule:PRU00237}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 13 interaction(s) predicted by orthology.
Predicted by orthology
Total 13 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000981 sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0001077 RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0005515 protein binding
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0006357 regulation of transcription from RNA polymerase II promoter
GO:0006366 transcription from RNA polymerase II promoter
GO:0007411 axon guidance
GO:0007517 muscle organ development
GO:0007638 mechanosensory behavior
GO:0030154 cell differentiation
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR000418 Ets domain
IPR006715 PEA3-type ETS-domain transcription factor, N-terminal
PFAM PF00178
PF04621
PRINTS PR00454
PIRSF
SMART SM00413
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q2KIC2
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 540846
UniGene Bt.87334
RefSeq NP_001039957
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC112692
GenPept AAI12693

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca