InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: PTRH2

Summary

InnateDB Protein

IDBP-681189.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

PTRH2

Protein Name

Peptidyl-tRNA hydrolase 2, mitochondrial

Synonyms

BIT1;

Species

Bos taurus

Ensembl Protein

ENSBTAP00000022212

InnateDB Gene

IDBG-629776 (PTRH2)

Protein Structure

UniProt Annotation

Function

The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis. {ECO:0000250}.

Subcellular Localization

Mitochondrion {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 15 interaction(s) predicted by orthology.

Predicted by orthology
Total	15 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004045	aminoacyl-tRNA hydrolase activity
GO:0005515	protein binding
GO:0016787	hydrolase activity

Biological Process

GO:0008152	metabolic process
GO:0010629	negative regulation of gene expression
GO:2000210	positive regulation of anoikis
GO:2000811	negative regulation of anoikis

Cellular Component

GO:0005739	mitochondrion
GO:0005829	cytosol
GO:0016020	membrane

Protein Structure and Domains

PDB ID

InterPro

IPR002833 Peptidyl-tRNA hydrolase, PTH2
IPR023476 Peptidyl-tRNA hydrolase II domain

PFAM

PF01981

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q3ZBL5

PhosphoSite

PhosphoSite-

TrEMBL

UniProt Splice Variant

Entrez Gene

516595

UniGene

Bt.13767

RefSeq

NP_001029691

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

AB238942 BC103230 BT021191

GenPept

AAI03231 AAX31373 BAF35578