InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: BRIP1

Summary

InnateDB Protein

IDBP-681451.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

BRIP1

Protein Name

BRCA1 interacting protein C-terminal helicase 1

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000053187

InnateDB Gene

IDBG-630001 (BRIP1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 21 interaction(s) predicted by orthology.

Predicted by orthology
Total	21 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0003676	nucleic acid binding
GO:0003677	DNA binding
GO:0004003	ATP-dependent DNA helicase activity
GO:0004386	helicase activity
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0008026	ATP-dependent helicase activity
GO:0016787	hydrolase activity
GO:0016817	hydrolase activity, acting on acid anhydrides
GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides

Biological Process

GO:0006139	nucleobase-containing compound metabolic process
GO:0006200	ATP catabolic process
GO:0006357	regulation of transcription from RNA polymerase II promoter
GO:0032508	DNA duplex unwinding

Cellular Component

GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0031965	nuclear membrane

Protein Structure and Domains

PDB ID

InterPro

IPR006554 Helicase-like, DEXD box c2 type
IPR006555 ATP-dependent helicase, C-terminal
IPR010614 DEAD2
IPR013020 DNA helicase (DNA repair), Rad3 type
IPR014013 Helicase, superfamily 1/2, ATP-binding domain, DinG/Rad3-type
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF13307
PF06733

PRINTS

PIRSF

SMART

SM00488
SM00491

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite