InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: KL

Summary

InnateDB Protein

IDBP-681506.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Protein Name

klotho

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000018586

InnateDB Gene

IDBG-630068 (KL)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.

Predicted by orthology
Total	11 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
GO:0004871	signal transducer activity
GO:0005104	fibroblast growth factor receptor binding
GO:0005515	protein binding
GO:0017134	fibroblast growth factor binding

Biological Process

GO:0005975	carbohydrate metabolic process
GO:0006112	energy reserve metabolic process
GO:0007568	aging
GO:0008286	insulin receptor signaling pathway
GO:0008543	fibroblast growth factor receptor signaling pathway
GO:0030501	positive regulation of bone mineralization
GO:0055074	calcium ion homeostasis
GO:0090080	positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway

Cellular Component

GO:0005615	extracellular space
GO:0016021	integral component of membrane
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

InterPro

IPR001360 Glycoside hydrolase, family 1
IPR017853 Glycoside hydrolase, superfamily

PFAM

PF00232

PRINTS

PR00131

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

E1BAI2

UniProt Splice Variant

Entrez Gene

784635

UniGene

Bt.106530

RefSeq

NP_001178124

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

DAAA02033072 DAAA02033073 DAAA02033074

GenPept