Version 5.4
Bos taurus Protein: FCGR2
Summary
InnateDB Protein IDBP-681532.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FCGR2
Protein Name Low affinity immunoglobulin gamma Fc region receptor II
Synonyms CD32; FCGR2; fcRII;
Species Bos taurus
Ensembl Protein ENSBTAP00000029114
InnateDB Gene IDBG-630039 (FCGR2)
Protein Structure
UniProt Annotation
Function Binds to the Fc region of immunoglobulins gamma. Low affinity receptor.
Subcellular Localization Cell membrane; Single-pass type I membrane protein.
Disease Associations
Tissue Specificity Higher expression is found in macrophages than in neutrophils.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0019864 IgG binding
Biological Process
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR003599 Immunoglobulin subtype
IPR007110 Immunoglobulin-like domain
PFAM
PRINTS
PIRSF
SMART SM00409
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q28110
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 282229
UniGene Bt.109697
RefSeq NP_776964
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL X75671
GenPept CAA53367

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca