InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: SRSF3

Summary

InnateDB Protein

IDBP-681586.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SRSF3

Protein Name

Serine/arginine-rich splicing factor 3

Synonyms

SFRS3;

Species

Bos taurus

Ensembl Protein

ENSBTAP00000049550

InnateDB Gene

IDBG-630146 (SRSF3)

Protein Structure

UniProt Annotation

Function

May be involved in RNA processing in relation with cellular proliferation and/or maturation. May function as export adapter involved in mRNA nuclear export such as of histone H2A. Binds mRNA which is thought to be transferred to the NXF1-NXT1 heterodimer for export (TAP/NXF1 pathway); enhances NXF1-NXT1 RNA- binding activity. RNA-binding is semi-sequence specific (By similarity). {ECO:0000250}.

Subcellular Localization

Nucleus {ECO:0000250}. Cytoplasm {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 92 interaction(s) predicted by orthology.

Predicted by orthology
Total	92 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0003676	nucleic acid binding
GO:0003723	RNA binding
GO:0005515	protein binding
GO:0044822	poly(A) RNA binding

Biological Process

GO:0006397	mRNA processing
GO:0006810	transport
GO:0008380	RNA splicing
GO:0051028	mRNA transport

Cellular Component

GO:0005634	nucleus
GO:0005737	cytoplasm

Protein Structure and Domains

PDB ID

InterPro

IPR000504 RNA recognition motif domain

PFAM

PF00076

PRINTS

PIRSF

SMART

SM00360

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q3SZR8

PhosphoSite

PhosphoSite-

TrEMBL

UniProt Splice Variant

Entrez Gene

540276

UniGene

Bt.87464

RefSeq

NP_001029872

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

BC102735

GenPept

AAI02736