InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: ANXA7

Summary

InnateDB Protein

IDBP-681599.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ANXA7

Protein Name

Annexin A7

Synonyms

ANX7;

Species

Bos taurus

Ensembl Protein

ENSBTAP00000046882

InnateDB Gene

IDBG-630152 (ANXA7)

Protein Structure

UniProt Annotation

Function

Calcium/phospholipid-binding protein which promotes membrane fusion and is involved in exocytosis.

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 94 interaction(s) predicted by orthology.

Predicted by orthology
Total	94 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005178	integrin binding
GO:0005509	calcium ion binding
GO:0005515	protein binding
GO:0005544	calcium-dependent phospholipid binding
GO:0042802	identical protein binding
GO:0044822	poly(A) RNA binding
GO:0048306	calcium-dependent protein binding

Biological Process

GO:0006874	cellular calcium ion homeostasis
GO:0006914	autophagy
GO:0007599	hemostasis
GO:0008283	cell proliferation
GO:0008360	regulation of cell shape
GO:0009651	response to salt stress
GO:0009992	cellular water homeostasis
GO:0010629	negative regulation of gene expression
GO:0030855	epithelial cell differentiation
GO:0035176	social behavior

Cellular Component

GO:0005634	nucleus
GO:0005635	nuclear envelope
GO:0005789	endoplasmic reticulum membrane
GO:0005829	cytosol
GO:0005886	plasma membrane
GO:0016020	membrane
GO:0031982	vesicle
GO:0042584	chromaffin granule membrane
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

InterPro

IPR001464 Annexin
IPR002391 Annexin, type IV
IPR013286 Annexin, type VII
IPR018502 Annexin repeat

PFAM

PF00191

PRINTS

PR00196
PR00200
PR01871

PIRSF

SMART

SM00335

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

P20072

PhosphoSite

PhosphoSite-

TrEMBL

UniProt Splice Variant

Entrez Gene

533360

UniGene

Bt.36610

RefSeq

NP_001069459

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

BC116141

GenPept

AAI16142