Version 5.4
Bos taurus Protein: ADAMTS5
Summary
InnateDB Protein IDBP-681728.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ADAMTS5
Protein Name A disintegrin and metalloproteinase with thrombospondin motifs 5
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000000849
InnateDB Gene IDBG-630284 (ADAMTS5)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004222 metalloendopeptidase activity
GO:0005515 protein binding
GO:0008237 metallopeptidase activity
GO:0008270 zinc ion binding
Biological Process
GO:0006508 proteolysis
GO:0042742 defense response to bacterium
Cellular Component
GO:0005578 proteinaceous extracellular matrix
GO:0031012 extracellular matrix
Protein Structure and Domains
PDB ID
InterPro IPR000884 Thrombospondin, type 1 repeat
IPR001590 Peptidase M12B, ADAM/reprolysin
IPR002870 Peptidase M12B, propeptide
IPR006586 ADAM, cysteine-rich
IPR010294 ADAM-TS Spacer 1
IPR013273 Peptidase M12B, ADAM-TS
IPR013276 Peptidase M12B, ADAM-TS5
PFAM PF00090
PF01421
PF01562
PF08516
PF05986
PRINTS PR01857
PR01860
PIRSF
SMART SM00209
SM00608
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL F1MRZ2
UniProt Splice Variant
Entrez Gene 286805
UniGene Bt.13108
RefSeq NP_001159987
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02000217 DAAA02000218 DAAA02000219
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca