InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: ME1

Summary

InnateDB Protein

IDBP-681793.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ME1

Protein Name

NADP-dependent malic enzyme

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000007465

InnateDB Gene

IDBG-630311 (ME1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004470	malic enzyme activity
GO:0004471	malate dehydrogenase (decarboxylating) (NAD+) activity
GO:0005515	protein binding
GO:0016491	oxidoreductase activity
GO:0030145	manganese ion binding
GO:0046872	metal ion binding
GO:0051287	NAD binding

Biological Process

GO:0006108	malate metabolic process
GO:0051262	protein tetramerization
GO:0055114	oxidation-reduction process

Cellular Component

GO:0005739

mitochondrion

Protein Structure and Domains

PDB ID

InterPro

IPR001891 Malic oxidoreductase
IPR012301 Malic enzyme, N-terminal domain
IPR012302 Malic enzyme, NAD-binding

PFAM

PF00390
PF03949

PRINTS

PR00072

PIRSF

PIRSF000106

SMART

SM00919

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

F1N3V0

UniProt Splice Variant

Entrez Gene

540985

UniGene

RefSeq

NP_001138325

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

DAAA02025495 DAAA02025496 DAAA02025497 DAAA02025498 DAAA02025499 DAAA02025500 DAAA02025501 DAAA02025502 DAAA02025503

GenPept