InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: ETFDH

Summary

InnateDB Protein

IDBP-681979.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ETFDH

Protein Name

Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000022178

InnateDB Gene

IDBG-630518 (ETFDH)

Protein Structure

UniProt Annotation

Function

Accepts electrons from ETF and reduces ubiquinone. {ECO:0000250}.

Subcellular Localization

Mitochondrion inner membrane {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004174	electron-transferring-flavoprotein dehydrogenase activity
GO:0009055	electron carrier activity
GO:0016491	oxidoreductase activity
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0046872	metal ion binding
GO:0048038	quinone binding
GO:0048039	ubiquinone binding
GO:0051536	iron-sulfur cluster binding
GO:0051539	4 iron, 4 sulfur cluster binding

Biological Process

GO:0006979	response to oxidative stress
GO:0016117	carotenoid biosynthetic process
GO:0022900	electron transport chain
GO:0033539	fatty acid beta-oxidation using acyl-CoA dehydrogenase
GO:0055114	oxidation-reduction process

Cellular Component

GO:0005739	mitochondrion
GO:0005743	mitochondrial inner membrane
GO:0016020	membrane
GO:0031305	integral component of mitochondrial inner membrane
GO:0031966	mitochondrial membrane

Protein Structure and Domains

PDB ID

InterPro

IPR002938 Monooxygenase, FAD-binding
IPR003953 FAD binding domain
IPR007859 Electron transfer flavoprotein-ubiquinone oxidoreductase
IPR008671 Lycopene cyclase-type, FAD-binding
IPR023753 Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain

PFAM

PF01494
PF00890
PF05187
PF05834
PF07992

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q2KIG0

PhosphoSite