Version 5.4
Bos taurus Protein: TARS
Summary
InnateDB Protein IDBP-682087.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TARS
Protein Name Threonyl-tRNA synthetase, cytoplasmic
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000018947
InnateDB Gene IDBG-630621 (TARS)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Cytoplasm {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 35 interaction(s) predicted by orthology.
Predicted by orthology
Total 35 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0004812 aminoacyl-tRNA ligase activity
GO:0004829 threonine-tRNA ligase activity
GO:0005524 ATP binding
GO:0016874 ligase activity
GO:0016876 ligase activity, forming aminoacyl-tRNA and related compounds
Biological Process
GO:0006412 translation
GO:0006418 tRNA aminoacylation for protein translation
GO:0006435 threonyl-tRNA aminoacylation
GO:0043039 tRNA aminoacylation
Cellular Component
GO:0005737 cytoplasm
GO:0015629 actin cytoskeleton
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR002314 Aminoacyl-tRNA synthetase, class II (G/ H/ P/ S), conserved domain
IPR002320 Threonine-tRNA ligase, class IIa
IPR004095 TGS
IPR004154 Anticodon-binding
IPR006195 Aminoacyl-tRNA synthetase, class II
IPR012676 TGS-like
IPR012947 Threonyl/alanyl tRNA synthetase, SAD
IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain
PFAM PF00587
PF02824
PF03129
PF07973
PRINTS PR01047
PIRSF
SMART SM00863
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q3ZBV8
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 510075
UniGene Bt.49332
RefSeq NP_001029542
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC103082
GenPept AAI03083

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca