InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: REXO2

Summary

InnateDB Protein

IDBP-682175.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

REXO2

Protein Name

Oligoribonuclease, mitochondrial

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000007680

InnateDB Gene

IDBG-630697 (REXO2)

Protein Structure

UniProt Annotation

Function

3'-to-5' exoribonuclease specific for small oligoribonucleotides. Active on small (primarily

Subcellular Localization

Mitochondrion intermembrane space {ECO:0000250}. Mitochondrion matrix {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.

Predicted by orthology
Total	6 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003676	nucleic acid binding
GO:0004518	nuclease activity
GO:0004527	exonuclease activity
GO:0008408	3'-5' exonuclease activity
GO:0016787	hydrolase activity
GO:0016788	hydrolase activity, acting on ester bonds

Biological Process

GO:0006139	nucleobase-containing compound metabolic process
GO:0008152	metabolic process
GO:0090305	nucleic acid phosphodiester bond hydrolysis

Cellular Component

GO:0005634	nucleus
GO:0005730	nucleolus
GO:0005739	mitochondrion
GO:0005758	mitochondrial intermembrane space
GO:0005759	mitochondrial matrix
GO:0005925	focal adhesion