Version 5.4
Bos taurus Protein: KERA
Summary
InnateDB Protein IDBP-682241.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol KERA
Protein Name keratocan precursor
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000019066
InnateDB Gene IDBG-630762 (KERA)
Protein Structure
UniProt Annotation
Function May be important in developing and maintaining corneal transparency and for the structure of the stromal matrix. {ECO:0000250}.
Subcellular Localization Secreted, extracellular space, extracellular matrix.
Disease Associations
Tissue Specificity Abundant in cornea and sclera but also found in other tissues. {ECO:0000269PubMed:9751803}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0061303 cornea development in camera-type eye
Cellular Component
GO:0005576 extracellular region
GO:0005578 proteinaceous extracellular matrix
Protein Structure and Domains
PDB ID
InterPro IPR000372 Leucine-rich repeat-containing N-terminal
IPR001611 Leucine-rich repeat
IPR003591 Leucine-rich repeat, typical subtype
PFAM PF01462
PF00560
PF13504
PF13855
PRINTS
PIRSF
SMART SM00013
SM00369
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O62702
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 280785
UniGene Bt.5391
RefSeq NP_776335
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL AF036962 BC120375 U48360
GenPept AAC48568 AAC69272 AAI20376

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca