InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: IL1R1

Summary

InnateDB Protein

IDBP-682303.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

IL1R1

Protein Name

interleukin 1 receptor, type I

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000006938

InnateDB Gene

IDBG-630765 (IL1R1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 34 interaction(s) predicted by orthology.

Predicted by orthology
Total	34 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0002020	protease binding
GO:0004871	signal transducer activity
GO:0004908	interleukin-1 receptor activity
GO:0004909	interleukin-1, Type I, activating receptor activity
GO:0005161	platelet-derived growth factor receptor binding
GO:0005515	protein binding

Biological Process

GO:0007165	signal transduction
GO:0019221	cytokine-mediated signaling pathway
GO:0050727	regulation of inflammatory response
GO:0070555	response to interleukin-1

Cellular Component

GO:0009986	cell surface
GO:0016020	membrane

Protein Structure and Domains

PDB ID

InterPro

IPR000157 Toll/interleukin-1 receptor homology (TIR) domain
IPR003599 Immunoglobulin subtype
IPR004074 Interleukin-1 receptor type I/II
IPR004076 Interleukin-1 receptor type 1
IPR007110 Immunoglobulin-like domain
IPR013151 Immunoglobulin

PFAM

PF01582
PF13676
PF00047

PRINTS

PR01536
PR01538

PIRSF

SMART

SM00255
SM00409

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt