Version 5.4
Bos taurus Protein: PAFAH1B2
Summary
InnateDB Protein IDBP-682341.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PAFAH1B2
Protein Name Platelet-activating factor acetylhydrolase IB subunit beta
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000007398
InnateDB Gene IDBG-630859 (PAFAH1B2)
Protein Structure
UniProt Annotation
Function Inactivates PAF by removing the acetyl group at the sn-2 position. This is a catalytic subunit.
Subcellular Localization Cytoplasm.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 24 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 24 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity
GO:0005515 protein binding
GO:0016787 hydrolase activity
GO:0016788 hydrolase activity, acting on ester bonds
Biological Process
GO:0006629 lipid metabolic process
GO:0007283 spermatogenesis
GO:0008152 metabolic process
GO:0016042 lipid catabolic process
GO:0016239 positive regulation of macroautophagy
Cellular Component
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR001087 Lipase, GDSL
PFAM PF00657
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P68401
PhosphoSite PhosphoSite-
TrEMBL V6F7P3
UniProt Splice Variant
Entrez Gene 282514
UniGene Bt.49728
RefSeq NP_777089
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC103452 D49678 GJ062397
GenPept AAI03453 BAA08534 DAA22363

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca